yeah, no problems here with car seats and leather. like jeff said, when you have kids i think it's best to have leather. clean up is so much easier.
i also put a towel under the car seat(s) and i strap them down pretty tight and haven't had any problems. my buddy just found mats for his MDX w/ leather seats that fit perfectly under his kids car seats. so i'll have to find out the brand and i'll post.
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